Alzheimer’s Disease

Alzheimer’s disease is a progressive mental disease that occurs due to the degeneration of the brain. It can manifest itself in the middle and old age thus causing premature senility. An interest in the disease arises from the fact that the condition affects a person’s cognitive ability. It raises the curiosity of how the brain changes to the extent that a healthy a functioning brain ends up damaged and almost non-functioning. A person that was once healthy and active may have Alzheimer’s disease, resulting in a loss of general body functioning. The cause of Alzheimer’s disease remains unknown although the early onset of the disease is associated with a genetic mutation. The late occurrence of Alzheimer’s disease, however, occurs due to a combination of genetic, environmental and lifestyle factors. People with APOE?4, have an increased of early onset of Alzheimer’s disease although people without the gene can also acquire the condition (Villemagne, & Ames, 2013).

Moreover, persons with Down syndrome have an increased risk of Alzheimer’s disease because of the existence of the extra chromosome 21 with the gene that produces the harmful amyloid. Conditions such as heart problems, diabetes, and high blood pressure have also been associated with a decline in cognitive functioning that increases the risk of Alzheimer’s disease. According to Qui & Strauss (2009), approximately 25 million people are affected by Alzheimer’s disease. In the Europe, the age-standardized prevalence in 65+ is 64% for dementia and 4.4% for Alzheimer’s disease. In America, the prevalence of Alzheimer’s disease in individuals over 70 years is 9.7%. The number of people who have Alzheimer’s disease is anticipated to double in the next twenty years.

The first symptom for persons with Alzheimer’s disease is a cognitive impairment that begins to manifest through memory loss. The memory loss may not be immediate, but the individual may start by demonstrating increased forgetfulness and repetition of statements. The mild cognitive impairment may be difficult to detect, but as the condition progresses, it becomes obvious. The individual may demonstrate complete memory loss; he may wander and get the loss (Jack, 2013). The individual may also take longer to perform tasks that he used to take a short duration to complete. In the severest form of the condition, the individual loses the ability to communicate and may not recognize family members.

The symptoms begin and vary with the changes that the brain is experiencing. Alzheimer’s disease is progressive thus the damage to the brain can begin decades before the symptoms begin to show. The brain begins to have abnormal deposits of amyloid plaques and tau tangles (Selkoe, & Hardy, 2016). The result is the healthy neurons stop functioning and lose connections with each other. Damage first begins at the hippocampus, the part responsible for formation of memory. The damage to the hippocampus marks the indicator of the first sign of Alzheimer’s disease, memory loss.

The diagnosis of Alzheimer’s disease involves a variety of test, examination and a look at the individual history. A physician may also perform a variety of tests to measure the patients, memory, problem-solving abilities, and language capacity. Laboratory tests such as urine and blood tests may be performed to eliminate other diseases that may manifest similar symptoms. Moreover, a CT, MRI, and PET test may be performed to rule out other possible causes of symptoms. Conditions such as stroke, brain tumors, and Parkinson’s diseases can expose an individual to symptoms such as those of Alzheimer’s disease.

There is no single intervention that is suitable for the management of Alzheimer’s disease. A patient may require a diversity of drugs and intervention to manage the condition (Liu & Shen, 2014). Currently, the emphasis is on helping patients maintain their mental function, manage their behavioral symptoms, and slow down the progression of the disease. There have been intensive studies to develop therapies that target the genetic, molecular and cellular mechanism of the disease. Medication such as donepezil, rivastigmine, and memantine are given to manage mild to severe Alzheimer’s. The drugs work by regulating the neurotransmitters, maintain thinking, memory and the patient’s communication skills. The medication does not work for all patients, while for others it may work for a while before they no longer do.

Unlike factors such as age and genetics that may be uncontrolled about the occurrence of Alzheimer’s disease, lifestyle and health factors can be controlled. Exercise and physical activity can ensure a healthy brain as the activities encourage the formation of blood vessels through the brain. Moreover, exercise and physical activity increase the number of connections between nerve cells thus ensuring a healthy brain. Exercise stimulates the brain thus keeping it healthy and less prone to degeneration. Scientists have also discovered that a healthy diet that is rich in vegetables reduces the rate of cognitive decline (Norton, & Brayne, 2014). Foods containing imega-3 fatty acids such as salmons and fish also reduce the occurrence of beta-amyloid plaques in the brain. Moreover, the engagement in mentally stimulating activities such as reading and engaging is sports activities reduce the risk of Alzheimer’s disease.

Welcome to SAP EHS: An Overview of Online Certification Programs

Organizations in various industries now prioritize workplace safety and environmental sustainability. As rules become more stringent, professionals who can effectively handle ecological and health concerns are in high demand. As laws become more stringent and public awareness of environmental and health concerns rises, professionals with effective management skills are desperately needed. SAP EHS (Environment, Health, and Safety) is applicable.

Just what is SAP EHS?

SAP EHS is a full suite of software products designed to assist companies in efficiently managing their safety, health, and environmental procedures. It offers the frameworks and instruments required for businesses to conduct themselves ethically, from guaranteeing regulatory compliance to reducing risks and promoting a safety culture.

Why is SAP EHS used?
Here are just a few advantages of implementing SAP EHS:
1. Assurance of Compliance: SAP EHS assists companies in adhering to health, safety, and environmental laws, lowering the possibility of fines and penalties.
2. Risk management: SAP EHS minimizes workplace events and accidents by proactively recognizing and reducing risks and safeguarding assets and personnel.
3. Operational Efficiency: Streamlining procedures with SAP EHS boosts productivity and efficiency while conserving time and resources.
4. Enhanced Reputation: Giving priority to environmental and workplace safety programs helps a firm be seen as a responsible corporate citizen while guaranteeing legal compliance.

SAP EHS Online Courses
Numerous online courses may be taken to suit different learning styles and ability levels if you’re interested in becoming an expert in SAP EHS. Here are a few well-liked choices:
1. Course Summary for SAP EHS: This course introduces SAP EHS and provides information on its modules and importance in the current corporate landscape.
2. Training for Implementing SAP EHS: Discover the steps involved in implementing SAP EHS solutions within your company, including integration customization with other SAP modules.
Learn about the ins and outs of incident reporting, investigation, and remedial action with SAP EHS Incident Management.
3. SAP EHS Compliance Management: Learn how to use SAP EHS tools and functions to ensure compliance with environmental, health, and safety requirements.
4. Investigate SAP EHS Reporting and Analytics: Discover how SAP EHS can be used for analytics and reporting, facilitating performance tracking and data-driven decision-making.

Certification for SAP EHS
Obtaining a SAP EHS certification improves your chances of landing a job while proving your competence. To become a qualified SAP EHS specialist, follow these steps:
1. Getting ready: Enroll in a thorough SAP EHS training course to get the required information and abilities.
2. Exam Registration: When ready, sign up for the SAP EHS certification exam using the SAP Training and Certification Shop.
3. Exam Planning: Use study materials, practice tests, and other resources to ensure you are well-prepared for the certification exam.
4. Exam: Attend a testing facility approved to administer the certification exam. Typically, the test consists of multiple-choice questions, and passing it is necessary to become certified.
5. Certification: If you complete the test, you will receive your SAP EHS certification, attesting to your expertise in the industry.

Engineering R and D Services Outsourcing Market – Outlook and Analysis for Future Growth

Global engineering R&D services outsourcing market is anticipated to reach more than USD 650 billion by 2025 according to a new report published by Polaris Market Research. The major factors which are driving this market is the access to low cost highly skilled resources which can work towards complex tasks of not only designing and testing but also on validation, simulation and execution. Companies are moving from business process outsourcing to knowledge process outsourcing and major industry verticals such as automotive, consumer electronics, semiconductors, aerospace and telecom are providing huge opportunities to the consulting companies.

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The traction of offshore outsourcing can be seen owing to the low cost and added capabilities from the service providers. There are dedicated ER&D service providers which are not only providing basic services but also, they are jointly investing with the companies to expand their businesses in growing markets and geographies. Companies are also focusing on expanding their market reach along with faster turnaround times from these providers. These are some of the major advantages for the companies to outsource their services.

The market for ER&D services has evolved from outsourcing of simple low-cost engineering services to capacity augmentation. At present companies are focusing more on reduced timelines, increased productivity and quality of outsourcing services. Countries such as India, China are among the biggest markets for ER&D service providers. Growing number of engineering professionals every year coupled with low cost of service have pushed the market for ER&D Outsourcing in this region.

Companies in North America and Europe are considered to spend more on these services however, Asia Pacific is the largest market for the ER&D service providers. Countries such as India and China have pushed the market for ER&D and are estimated to continue the trend over the forecast period. Applications in the automotive, telecom, consumer electronics and aerospace segments is considered to have large market share in 2017. There has been an increase in adoption in the offshore services as compared to onsite service due to low costs and highly skilled professionals on the offshore locations. The offshore outsourcing type would grow at a higher rate during the forecast period as compared to its counterpart.